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The Role of the Subjective Experience in Supporting Positive Effects Following Psilocybin: a Randomized, Controlled Clinical Trial Using Risperidone in Healthy Adults

The purpose of this study is to determine the importance of the acute subjective experience induced by psilocybin (the primary component of "magic mushrooms") in facilitating positive outcomes. Participants in this study will be given psilocybin in combination with either a placebo or risperidone, an atypical antipsychotic that block the subjective effects of psilocybin.

Status
recruiting
Phase
Phase 2
Institution
University of Calgary
Principal investigator
Leah Mayo, PhD
Start date
2026-05-15
End date
2028-01-01
Registry ID
NCT06768944

View trial record

Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.