Investigating the Role of the Psychedelic Experience in the Antidepressant Response in Patients With Major Depression: a Placebo-controlled Factorial Trial With DMT Masked With Propofol (DMT4D-Study)
The aim of this study is to elucidate if the anti-depressive effect of N,N-dimethyltryptamine (DMT) is based on a biological mechanisms including neuroplasticity and anti-inflammatory effect or due to the subjective psychedelic experience.
- Status
- recruiting
- Institution
- University Hospital, Basel, Switzerland
- Principal investigator
- Matthias Liechti, Prof. Dr. med.
- Start date
- 2025-08-05
- End date
- 2029-03-01
- Registry ID
- NCT06927076
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.