Neural Circuit-Specific Mechanisms of Ketamine's Effect on Anhedonia and Anxiety in Depression Using Ultra-High Field 7-Tesla MRI
This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and depression symptoms.
- Status
- recruiting
- Phase
- Phase 4
- Institution
- Icahn School of Medicine at Mount Sinai
- Principal investigator
- James Murrough, MD/PhD
- Start date
- 2024-01-31
- End date
- 2028-04-30
- Registry ID
- NCT06213324
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.