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The Effects of Psilocybin on Social Connectedness

The study is a randomized, double-blind, placebo-controlled, expectancy-controlled, mechanistic trial. This study looks to explore whether a single dose of psilocybin (25mg) reduces amygdala reactivity to negative socioemotional stimuli during the Facial Emotion Recognition Task (FERT) compared to a placebo in adults who feel lonely or those with unresolved grief symptoms.

Status
planned
Phase
Phase 1
Institution
Yale University
Principal investigator
Anahita Bassir Nia, MD
Start date
2026-08-31
End date
2031-12-15
Registry ID
NCT07693153

View trial record

Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.