Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
The purpose of this study is to identify pharmacokinetics of postpartum ketamine infusion. This study will assess ketamine kinetics and metabolism in this setting. Ketamine is expected to exert different kinetics during the physiologic state of post-pregnancy. The goal in conducting this study is to better understand the pharmacokinetics and pharmacodynamics of postpartum ketamine infusion. A secondary goal is to compare these kinetics to reproductive age matched controls and to assess sex differences in ketamine pharmacokinetics. The peripartum group of this study will receive ketamine after cesarean delivery, while the control group will consist of non-pregnant female subjects and male subjects receiving the same infusion protocol.
- Status
- suspended
- Phase
- Phase 1
- Institution
- University of Utah
- Principal investigator
- Grace Lim, MD, MSc
- Start date
- 2025-03-28
- End date
- 2028-03-01
- Registry ID
- NCT06767566
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.