Psilocybin Administration With 5-HT1a Blockade
The purpose of this study is to assess the effects of 5-HT1A receptor blockade on the acute subjective effects of psilocybin, as measured through subjective survey measures and acute electroencephalography (EEG). Further, the investigators will assess the effects of psilocybin on post-acute sleep and dreaming through the use of sleep EEG and sleep and dream diaries.
- Status
- recruiting
- Phase
- Early Phase 1
- Institution
- Johns Hopkins University
- Principal investigator
- Sandeep M Nayak, MD
- Start date
- 2026-08-01
- End date
- 2028-06-15
- Registry ID
- NCT07565493
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.