Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in a Randomized, Placebo-controlled, Cross-over Trial in Healthy Participants (LPD-Study)
The primary objective of this study is to determine whether equivalent moderately high doses of LSD, psilocybin, and DMT produce qualitatively similar peak effects when the effect duration is standardized with ketanserin. A DMT infusion mimicking oral LSD and psilocybin administrations will be tested, as well as intravenously administered ketanserin.
- Status
- recruiting
- Phase
- Phase 1
- Institution
- University Hospital, Basel, Switzerland
- Principal investigator
- Matthias E Liechti, Prof. Dr. MD
- Start date
- 2025-04-01
- End date
- 2026-08-01
- Registry ID
- NCT06899334
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.