A Randomized Trial to Compare MDMA-assisted Cognitive Processing Therapy (aCPT) Versus a VA Standard-of-care CPT for the Treatment of Severe Posttraumatic Stress Disorder Among Veterans
In partnership with the Veterans Affairs (VA) Palo Alto Health Care System and Stanford University, this study aims to evaluate clinical outcomes, assess implementation feasibility, and health economics of MDMA-assisted Cognitive Processing Therapy (MDMA-aCPT) in the treatment of posttraumatic stress disorder (PTSD). Through a randomized comparison of MDMA-aCPT versus Cognitive Processing Therapy (CPT), a VA gold standard treatment for PTSD, the proposed study will set the stage for understanding the potential use and application of MDMA-aCPT for PTSD within the VA system.
- Status
- recruiting
- Phase
- Phase 2
- Institution
- Patricia Suppes
- Principal investigator
- Trisha Suppes, MD, PhD
- Start date
- 2025-02-10
- End date
- 2027-12-01
- Registry ID
- NCT05837845
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.