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Pilot Clinical Trial of Ketamine-assisted Psychotherapy for Methamphetamine Use Disorder and HIV Risk Reduction

The goal of this clinical trial is to learn whether it is possible to use intramuscular (IM) ketamine in combination with psychotherapy to treat moderate-to-severe methamphetamine use disorder (MeUD) in publicly insured patients with or at-risk for HIV disease. The main questions it aims to answer are: * Do publicly insured patients find ketamine-assisted psychotherapy feasible and acceptable as a potential treatment for MeUD? * Is IM ketamine safe and tolerable among patients with MeUD? Participants will: * Receive 3 monitored doses of IM ketamine * Have 3 preparation and 4 integration psychotherapy visits * Report their daily amounts of methamphetamine used prior to, during, and up to 3 months following the intervention

Status
active
Phase
Phase 2
Institution
Nicky Mehtani, MD, MPH
Principal investigator
Nicky Mehtani, MD MPH
Start date
2025-03-04
End date
2026-07-01
Registry ID
NCT06538285

View trial record

Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.