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The Safety and Acceptability of Psilocybin With Support and With Massed Prolonged Exposure Therapy for PTSD

This pilot study will examine the safety, tolerability, acceptability, and efficacy of combination psilocybin + psychotherapy to decrease PTSD symptoms. Participants will be randomized into two different treatment groups, allowing the investigators to directly compare PE augmented with psilocybin and psilocybin-assisted psychotherapy.

Status
planned
Phase
Phase 2
Institution
Emory University
Principal investigator
Anna Wise, PhD
Start date
2026-06-01
End date
2027-03-01
Registry ID
NCT07332143

View trial record

Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.