Activating Neuroplasticity to ENHANCE the Perception Box Expanding Effects of Psilocybin
This study will examine whether combining a single dose of psilocybin with non-invasive transcutaneous auricular vagus nerve stimulation (taVNS), a potential inducer of neuroplasticity and enhanced memory formation, will enhance the long-term beneficial behavioral effects of psilocybin when compared to sham taVNS or no VNS by allowing memory for insights gained during the psychedelic experience to remain vivid after they will have faded in subjects who receive psilocybin followed by sham taVNS or no VNS.
- Status
- recruiting
- Phase
- Phase 1
- Institution
- University of Wisconsin, Madison
- Principal investigator
- Charles Raison, MD
- Start date
- 2025-01-27
- End date
- 2028-01-01
- Registry ID
- NCT05866471
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.