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Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

This study is exploring how psilocybin (a psychedelic drug) may improve mood and wellbeing. Many people report feeling better after taking psilocybin, but it is not clear why. The CoPEWell study will test whether these improvements come from the psychedelic experience itself (the "trip") or from direct effects on the brain. To study this, up to 120 participants will be enrolled to receive psilocybin either while awake or asleep and can expect to be on study for up to 4 months.

Status
planned
Phase
Phase 1
Institution
University of Wisconsin, Madison
Principal investigator
Charles Raison, MD
Start date
2026-09-01
End date
2028-02-01
Registry ID
NCT07360301

View trial record

Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.