Acute Analgesic Effects of 3,4-methylenedioxymethamphetamine (MDMA) on Experimentally Induced Acute Nociceptive Pain, Hyperalgesia and Allodynia in Healthy Participants (MDPS-study)
This study investigates whether MDMA may have a pain-reducing effect. The effect of MDMA is compared with a placebo (a substance with no active effect). In the study, moderate pain will be artificially created in healthy participants using repeated small electrical pulses applied under the skin. At the same time, participants will take MDMA or a placebo by mouth. This allows researchers to compare how MDMA affects the artificially created pain. A total of 20 healthy volunteers will take part in this study.
- Status
- recruiting
- Phase
- Phase 1
- Institution
- University Hospital, Basel, Switzerland
- Start date
- 2026-03-09
- End date
- 2027-04-09
- Registry ID
- NCT07494214
Tracked by the DMT Code Clinical Trials Observatory, an open record of DMT-related clinical research.